Doc Ock, Sinister Scientist

As long as there are eight or more cards in your graveyard, Doc Ock has base power and toughness 8/8.
As long as you control another Villain, Doc Ock has hexproof. (He can't be the target of spells or abilities your opponents control.)

Aunt May

Whenever another creature you control enters, you gain 1 life. If it's a Spider, put a +1/+1 counter on it.

Doc Ock's Henchmen

Flash
Whenever this creature attacks, it connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on this creature.)

Flying Octobot

Flying
Whenever another Villain you control enters, put a +1/+1 counter on this creature. This ability triggers only once each turn.

Hide on the Ceiling

Exile X target artifacts and/or creatures. Return the exiled cards to the battlefield under their owners' control at the beginning of the next end step.

Hydro-Man, Fluid Felon

Whenever you cast a blue spell, if Hydro-Man is a creature, he gets +1/+1 until end of turn.
At the beginning of your end step, untap Hydro-Man. Until your next turn, he becomes a land and gains "{T}: Add {U}." (He's not a creature during that time.)

Impostor Syndrome

Copy

Whenever a nontoken creature you control deals combat damage to a player, create a token that's a copy of it, except it isn't legendary.

Lady Octopus, Inspired Inventor

Whenever you draw your first or second card each turn, put an ingenuity counter on Lady Octopus.
{T}: You may cast an artifact spell from your hand with mana value less than or equal to the number of ingenuity counters on Lady Octopus without paying its mana cost.

Madame Web, Clairvoyant

You may look at the top card of your library any time.
You may cast Spider spells and noncreature spells from the top of your library.
Whenever you attack, you may mill a card. (You may put the top card of your library into your graveyard.)

Mysterio, Master of Illusion

Illusion Villain

When Mysterio enters, create a 3/3 blue Illusion Villain creature token for each nontoken Villain you control. Exile those tokens when Mysterio leaves the battlefield.

Mysterio's Phantasm

Flying, vigilance
Whenever this creature attacks, mill a card. (Put the top card of your library into your graveyard.)

Norman Osborn

Norman Osborn can't be blocked.
Whenever Norman Osborn deals combat damage to a player, he connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on this creature.)
{1}{U}{B}{R}: Transform Norman Osborn. Activate only as a sorcery.

Green Goblin

Flying, menace
Spells you cast from your graveyard cost {2} less to cast.
Goblin Formula — Each nonland card in your graveyard has mayhem. The mayhem cost is equal to its mana cost. (You may cast a card from your graveyard for its mayhem cost if you discarded it this turn. Timing rules still apply.)

Norman Osborn // Green Goblin

Food

City Pigeon

Flying
When this creature leaves the battlefield, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this token: You gain 3 life.")

Oscorp Research Team

Robotics Mastery

Robot

Flash
Enchant creature
When this Aura enters, create two 1/1 colorless Robot artifact creature tokens with flying.
Enchanted creature gets +2/+2.

School Daze

Choose one —
• Do Homework — Draw three cards.
• Fight Crime — Counter target spell. Draw a card.

Marvel's Spider-Man